PSL201Y1 Lecture Notes - Lecture 1: Electrochemical Gradient, Membrane Transport Protein, Lipid Bilayer
Document Summary
She passed 2000 ml of urine and increased her serum to 125 mmol/l 2 hours after infusion, which then returned to normal the next morning. Average person has about 42l of water in the body (60% of body weight). Interstitial: water in tissues, water that bathes cells/tissue. Some areas of the lipids are water-soluble such as ions, glucose, amino acids, and water (hydrophilic), and areas that are not such as fats (hydrophobic). Hydrophobic substances allow crossing of the phospholipid bilayer. Simple diffusion: movement of solute down concentration gradient: rate = constant x area/distance (c1-c2, c1-c2 is the concentration gradient, also depend on permeability of membrane how soluble a substance can move across phospholipid bilayer, ex. Co2 can diffuse faster than o2: ex. Facilitated diffusion: movement down electrochemical gradient from high to low with use of channels: types of membrane transport proteins: Carriers: membrane protein hat bind to a molecule to change position and allow for transport (ex.