PCL200H1 Lecture Notes - Lecture 12: Slow-Wave Sleep, Absence Seizure, Generalised Tonic-Clonic Seizure

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15 May 2020
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Every brain has a seizure threshold", and if you have enough excitation it"ll lead to a seizure. Seizures are triggered in non-epileptic people during electroconvulsive therapy (ect) About 1% of population has epilepsy at any given time (point prevalence) About 4% of population will have epilepsy at some point in their lifespan. Genetic - 70% - due to mutation in a gene that controls neuron excitability. E. g. , brain tumor, trauma with scar, vascular malformation - you can point to it and say that"s why you have seizure. Most commonly diagnosed in children before age 15. Some of those children will outgrow seizures. Co-morbidities (suffering from other disorders along with seizures) Psychiatric - anxiety, depression, adhd, psychosis (similar to schizophrenia) Also co-morbities for asthma, migraine, stroke, ulcers. Tonic clonic (grand mal) - unconscious, dramatic convulsions, no memory of attack, lasts less than 5 minutes, constant spiking throughout whole brain. Occur in just one location of cortex.

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