JNH350H1 Lecture Notes - Lecture 4: Coinfection, Hypersexuality, Hookworm Infection
Document Summary
Dominant views of western analysts: frequency of sexual encounters, number of sexual partners, ideas of african hypersexuality. Stillwaggon refutes these arguments with detailed data countering the conventional wisdom. If hypersexuality is not the predominant cause of the high rates of hiv in parts of. In a discordant couple, (one hiv+, the other hiv-) what is the probability of hiv transmission in a single sex act: male negative, female positive: 1/1000, male positive, female negative: 1/500. Unprotected heterosexual intercourse between otherwise healthy adults is a relatively inefficient mode of hiv transmission. Key factors severely compromise immune response: endogenous variables, malnutrition, parasite burden, coinfections. Broader political economic variables (the four horsemen of the apocalypse: poverty, war, economic disruption, rapid urbanization. Malnutrition: increase susceptibility to infection: protein malnutrition, energy malnutrition, pem protein and energy malnutrition, micronutrients, iron, zinc, vitamin a, impact on infectious disease, example: vitamin a and std. Case study: vitamin a deficiency and immune response.
