MGY277H1 Lecture Notes - Lecture 11: Phagolysosome, Streptolysin, Phagosome
2 Apr 2017
School
Department
Course
Professor
Document Summary
Colonization the microbe establishing itself on/in body surface or mucosal layer. Infection can be used to refer to colonization by a pathogen. Infectious disease or illness noticeable impairment in a person. Symptomes subjective effects experienced by patients (e. g pain and nausea) Signs objective evidence (e. g rash, swelling) can be physically measured. Damage can predispose individual to secondary infection (e. g measles impairs immune system leading to pneumonia by other microbes) Primary pathogen microbe or virus that causes disease in otherwise healthy individual. Diseases such as plague, malaria, measles, influenza,etc. Opportunistic pathogen (opportunist) casue disease only when body"s innate or adaptive defenses are compromised or when introduced into unusual location. Can be members of normal microbiota or common in environment. Virulence factors traits that allow microorganisms to casue disease (e. g toxic a microbe produces) Attribute of a microbe that promote pathogenicity. Infectious dose number of microbes necessary to establish infection (an experimentally derived number)
