IMM250H1 Lecture Notes - Lecture 5: Tak Wah Mak, Peripheral Tolerance, T-Cell Receptor
105 views4 pages
Document Summary
Lecture 5 - dr. tamminen (start of adaptive immune system- special features) There are innate cells (inborn, unchanging) and adaptive cells (imrives over time in response to circumstances). In ammation is what activates the adaptive immunity reponse. Lymphocytes are the cells of the adaptive immunity. There are various types of lymphocytes including b cells and t cells. We are focusing on conventional t cells and b cells which are the majority. After a pathogen enters there is recognition a response and then a return to resting occurs in adaptive immunity as well. There is a small region on the antigen called the epitope that is bound by lymphocyte antigen receptor. The b cell receptor is called immunoglobin (ig). B cells when activated secrete ig in the form of an antibody. There are 2 chains that form the t cell receptor a beta chain and an alpha chain and 2 binding sites aswell.
Get access
Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers
Related Documents
Related Questions
There are a variety of lymphocytes involved in the adaptiveresponse, each with a specific function. One of the subsets ofcells essential in the adaptive response is T helper cells. Choosethe answer that most accurately describes the role of T helpercells in mounting the antibody response.
Select the best answer.
T helper cells present antigens to B cells, which is requiredfor their activation. | |
T helper cells aid in the response by killing infected cellswhile the antibody response mounts. | |
T helper cells aid the antibody response by binding to the Bcell MHCII/protein complex and secreting cytokines like IL-4. | |
T helper cells secrete IL-2, which is required for clonalexpansion of B cells. Please explain why! |