CHM136H1 Lecture Notes - Lecture 34: Ketone, Leaving Group, Formaldehyde

• School: UTSG
• Department: Chemistry
• Course: CHM136H1

Document Summary

Memorize ir spectra - no table will be given. Bc reaction causes grignard to yield hc and mg salt. Grignard acts exclusively as a lewis base in this reaction. Bronsted base would attach proton adjacent to ester. Can"t be prepared if other reactive functional groups are present in same molecule. Think of these reagents as simply :r- (carbon is a nucleophile) Primary or secondary converted into halides via sn2 with socl2 or pbr3. Better leaving group creation leads to production of nucleophile. But it isn"t universal, just a rule of thumb. Follows zaitsev"s rule and yields more stable alkene. Otherwise it will conflict with the desired product. Oxidation of alcohols (17. 7: this creates double bonds initially, for the primary alcohol, the carboxylic acid is favoured ultimately. Chm138h1 notes page 2: for the primary alcohol, the carboxylic acid is favoured ultimately. Special reagent is required if an aldehyde is desired.