BCH210H1 Lecture Notes - Lecture 3: Hemoglobin, Globular Protein, Quaternary

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Stavroula Andreopoulos

Document Summary

The structure of a protein is its amino acid sequence. The order of these amino acids matter and the order is dictated by the dna. Secondary structure is how these amino acids are arranged into additional conformational states. Teraitary is one polypeptide that forms helixes that fold together to form a globular protein. The alpha helix is stabilized by hydrogen bonds and the h bonds are in the backbone itself. Side chains have an impact on if the amino acids form a helix. The side chains point towards the n terminus and the side chains are on the utside. The hydrogen bond from r5 binds to the c=o, meaning its very far away. It binds because the protein folds up so they are in close proximity where they can then bind. In a helix, r5 is close to r1. Water is displaced inside the helix and it allows the h bonding to form.