BCH210H1 Lecture Notes - Lecture 20: Oxidoreductase, Isocitric Acid, Coenzyme Q10
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As soonye follows her 10 km training run, she approaches the eastern end of the board walk and the hill near the filtration plant. Soonyes muscle will yield pyruvate using both free glucose form her blood and also glucose units from glycogen breakdown. You can appreciate the small but important yields of atp that comes from glycolysis in substrate level phosphorylation reaction. Today we want to begin our discussion of mitochondrial oxidative powerhouse that will produce a considerable amount of. Specifically today we will consider the reactions of pyruvate dehydrogenase or pdh complex and the citric acid cycle. When pyruvate enters the mitochondria, it enters an oxidative path that ultimately relies on the presence of oxygen. The initial reaction is carried out by the pyruvate dehydrogenase or pdh complex that converts pyruvate to acetyle. This activated acetyl group can then enter citric acid cycle.
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