ANA300Y1 Lecture Notes - Lecture 6: Irregular Bone, Central Canal, Sesamoid Bone

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20 Feb 2013
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Bone is used for physical support, leverage, protection of internal organs (like the brain), storage of minerals (calcium phosphate) and lipids), and the protection of blood cells (hematopoiesis) A third of your bone is organic matter, it"s not all calcium. There"s osteoid and it"s maid mostly of collagen type i (eosinophilic and it"ll stain very pink). There are also components of glycoproteins and proteoglycans. These molecules are much smaller compared to collagen, meaning there is less tissue fluid. There is tissue fluid (fluid between blood and cells). The organic component of the bone matrix resists pull (provides tensile strength) and it endows flexibility. Without the organic component, it"ll be very fragile. Two thirds of the bone is inorganic. It is mainly calcium and phosphate (hydroxyapatite; hydroxyl molecule). This component of the bone provides compressional strength and mineral storage (where calcium phosphate is stored).

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