PHLB09H3 Lecture Notes - Lecture 12: Biopsy, Primum Non Nocere

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Theoretical equipoise: theoretical equipoise: a physician is indifferent between two proposed treatments. For example, an experimental therapy or standard therapy: not following this equipoise can violate the principle of beneficence, clinical equipoise: there is a disagreement in the medical community regarding which therapy ought to be preferred. Theoretical equipoise: fragility: indifference between two possible treatments can be disturbed, difficult to measure, idiosyncratic: physician"s intuition or hunch can put them out of equipoise (the state of being indifferent) Clinical equipoise: reflects our standards of competent medicine. A critique of clinical equipoise: miller & brody: they are against freedman"s idea: research is an extension of therapy, therapeutic misconception: research isn"t a form of therapy, brock and brody said this. Beneficence: beneficence is in practice, violated, consider treatment for depression, therapeutic considerations, dosage amount (individual, based on each individual"s needs, dosage change (individual, other interventions (individual)

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