NROD67H3 Lecture Notes - Lecture 8: Zeitgeber, Lean Body Mass, Prolactin

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Antioxidants such as resveratrol have been shown to decrease ros production. Ros is thought to contribute to the aging process by inducing cell damage and thus, antioxidants have been recommended to help prevent. Double agent superoxide acts like double agent cause damage cell/proteins/fat which can lead to aging but can also play fundamental role in cell signalling/immunity. Cells need to keep enough antioxidants to prevent damage but cannot have too much antioxidants because can interfere with signalling and immunity. Huhn et al. (2015) components of a mediterranean diet and their impact on aging. Impact of omega-3 fatty acids on the brain: Med diet = high intake of unsaturated fatty acids (long chain omega 3 polyunsaturated fatty acids - lc n3 fa) Epa and dha: found in mackerel and salmon astrocytes in brain are major site for processing lcn3fa. Dha and epa: lower dementia risk (humans, better cognitive performance (humans, improved learning and memory (rodents, reduced amyloid burden (mice)

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