NROC64H3 Lecture Notes - Lecture 7: Excitatory Synapse, Brainstem, Cytosol
17 Mar 2012
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Motor system: muscles and neurons that control muscles. Parts of motor control: spinal cord coordinated movements, brain motor programs in sc. Types of muscles: smooth: digestive tract, arteries, related structures, striated cardiac/heart and skeletal/bulk of body muscle mass. Somatic musculature (skeletal: axial trunk movement, proximal shoulder, elbow, pelvis, knee movement, distal: hands, feet, digits movement. = lower motor neuron: innervated by ventral horn of sc. Upper motor neuron: supplies input to sc. Dorsal ventral: flexors extensors (think of example on right) 2 lower motor neurons alpha and gamma. Motor unit = alpha neuron + muscle fiber(s) Motor neuron pool: populations of lower motor neurons innervating 1 muscle. Neurons: varying firing of motor neurons: more ach release, temporal summation, recruit additional synergistic motor units, small and large motor neurons (more muscle fibers) Alternate nerve input switch in muscle phenotype. /physical characteristics. Als: loss of large a-neurons, loss of superoxide dismutase increase in superoxdice radical?.
