HLTB22H3 Lecture Notes - Lecture 6: Mucous Membrane, Botulism, Genetic Engineering

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Physical barriers: chemical barriers, 2nd line of defence, 3rd line of defence, antibody mediated, cell mediated, 1. Specific defences dif cells of defence: 6. Withdrawal: ^on final, pathogens, microbial world, increase in noncommunicable diseases chronic, internal agencies relate to chronic conditions, infectious diseases still cause significant amt of deaths globally. Pathogens: disease causing organisms, include: bacteria, viruses, protozoans, fungi, parasitic worms & prions, virulence, relative ability of pathogen to cause disease, determined by: Symptoms of disease depend on which cells are killed. Slow release of new viruses allows cell to remain alive & continue to reduce new viruses for prolonged period: latent infection, delay b/w infection & symptoms, virus present in cell w/ out harming cell. Symptoms begin when virus starts to actively replicate & new viruses exiting host cell can cause cell death: primary infection, latent period, secondary infection, transformation to cancerous cell, certain viruses insert genetic info into host cell chromosomes.

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