EESA10H3 Lecture Notes - Lecture 9: Biomagnification, Organism, Reproductive Toxicity
Document Summary
Fate: chemical or physical transformation of contaminants in the environment. Transport: movement of contaminants within or between environmental medial. Fate and transport of chemicals is affected by their physical-chemical properties. How harmful a substance is depends on physical-chemical properties of substances. Volatility, electronegativity, polarity, solubility (water soluble toxins/fat soluble toxins (lipophilic tendency), oxidation state, dissociation, molecular weight. Generally, higher molecular weight chemicals are more lipophilic and persistent and less volatile and less water soluble. Persistence in environment: quantified as a half-life in air, water soil, affected by environmental conditions. Introduction to toxicology the science of the effects of toxic substances and of their fate and transport in body. Study of poison: science which studies toxic substance or poisons, that are substances which causes alteration or perturbation in the function of an organism leading to harmful effects: o o o o o o.