EESA10H3 Lecture Notes - Lecture 5: Ionic Bonding, Covalent Bond, Lead
20 Mar 2019
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Document Summary
Heavy metals: naturally occurring, extracted from the earth, in ore, wide environmental dispersion, tendency to accumulate in select tissues, toxic in even low concentrations. Mechanism of toxicity: blocking essential functional groups in proteins or enzymes; proteins cannot carry anything, displace other metals (class b, borderline, modifying the active conformation of biomolecules (class b) Internal detoxifying mechanisms: binding to non-sensitive compound structures, metabolic transformations to less toxic forms (methylation of as in marine biota, can develop multiple tolerance cu, pb, zn, cd. Inhalation (dust or pm, fume, gas) from the air. It was caused by the release of methylmercury in the industrial wastewater from the. Chisso corporation"s chemical factory, which continued from 1932 to 1968: this highly toxic chemical bioaccumulated in shellfish and fish in minamata bay and the. Shiranui sea, which when eaten by the local population resulted in mercury poisoning. Cat, dog, pig and human deaths continued over more than 30 years.
