EESA10H3 Lecture Notes - Lecture 4: Miscarriage, Bisphenol A, Phthalate

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Outline: endocrine disrupters, health implications, neurobehavioral implications, chemical body burdens, organochlorine substances, dioxins, ddt, phthalate and bisphenol a. Endocrine disrupters neurobehavioral implications: prenatal and early postnatal exposures, pcbs (polychlorinated biphenyls): Iq and motor skills are a little lower. Chemical body burdens total quantity of chemicals present in the human body (plural! Nobody has none: compared to individuals who live at a place that is not exposed a lot (occupation chemical, mining industry, neighbour, regular use of instrument that uses radioactive etc. ) Will not represent a normal background : to be able to see how much we have/how many we have we need a reference/standard. Organochlorine substances: dioxins, ddt, phthalate and bisphenol a. Increased heart disease and diabetes: causes immunosuppression, study in mice showed ability to cause birth defects (teratogenicity, chloracne. In 1991, the us exported 92 tons of ddt. In at least 26 countries, ddt is completely banned, and in 12 others it is severely restricted.

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