CHMA10H3 Lecture Notes - Lecture 1: Electron Affinity, Bond Length, Effective Nuclear Charge
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CHMA10H3 Full Course Notes
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Document Summary
Hemoglobin contains porphryin, carries molecular(triplet) oxygen, second (singlet) from of oxygen is highly toxic, energetic states separate the two. Triplet oxygen is a ground state, singlet possesses more energy. Singlet oxygen stops cell division and kills cells. Singlet oxygen needs to produced right where it is needed. Porphyrins are coloured and not only interact with oxygen, can go from ground to excited state after interacting with photons. Patient is given a dose of photosensitizer, the light is then applied to the target site, singlet oxygen is formed and kills cancer. Photodynamic therapy is highly targeted, singlet oxygen that doesn"t react degrades back to triplet oxygen, a timed poison, very effective. Photodynamic therapy created positive effects in patients vision. Two slightly different isomers of porphyrins are used as photosensitizers in. Different wavelengths excite the isomers and enhances penetration depth of light and range of light used. Porphyrins dissipate in the body and get secreted out rapidly.
