BIOC65H3 Lecture Notes - Lecture 5: Sympatholytic, Atenolol, Visine

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12 Oct 2016
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Last time we started discussing the process of inflammation and there are many gateways for it. One of which is through histamine its an amine binding to receptors (bunch of them but most important is h1 (we only mention h2, h3, So the three vascular symptoms are vasodilation, vascular permeability and extravasation are the 3 symptoms of imflammation as induced by histamine release. We can get it without histamine by bypassing this step and through enhanced prostaglandins release. Recall: the 3 macroscpic inflammation signs the reddening (erythema) , the swelling (edema), the itch( pruritis) /pain (dolor) H receptors antagonisctically and not allowing histamine to bind) all the time so they can live a normal life. Anti-histamine: caffiene (not a direct anti-histamine itself), reactine (cetirizine new generation of antihistamie that don"t make you drowsy anti histamines make you drowsy if it crossed the blood brain barrier.

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