BIOC39H3 Lecture Notes - Lecture 2: Cfu-Gemm, Lymphopoiesis, Hematopoietic Stem Cell
Document Summary
Hematopoietic system refers to the cells of the immune system. Within the last 5 years, there have been more cell types that have been discovered: won"t really focus on the subtypes, although we"ve known the (cid:883)(cid:883) main cell types for a couple of years, we. Basically what we refer to as the process of blood cell: the site of hematopoiesis changes with age from the embryo to the. Early embryo takes place in the yolk sac and fetal liver (cid:523)~(cid:885)-5 months) ~ 5 month fetus it shifts to bone marrow. The site of hematopoiesis in bone marrow is the skull, ribs, sternum, Some development in smaller bones, but these are the main sites of vertebral column, pelvis, and femurs hematopoiesis in bone marrow cells (hsc) adult. Total potency which is really in the embryo. Hematopoietic stem cells sit at the interface of what some people would call pluripotent and other would consider multi- potent different cells.