BIOC34H3 Lecture Notes - Lecture 16: Distal Convoluted Tubule, Ascending Limb Of Loop Of Henle, Oncotic Pressure

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4 Jan 2018
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Lecture 16: the renal system & kidney function: pressures driving fluid in and out of capillaries, standard capillary bed pressure differentials force fluid from the capillaries into the interstitial (extracellular) fluid, hydrostatic pressure gradient: Pressure exerted by the presence of a fluid in a system. Capillary: hydrostatic pressure = blood pressure in capillaries. They force fluid out of capillary and into the ecf both. Ecf: arterial side hp > op, venous side hp < op, net filtration pressure: leads to fluid movement across the capillary. Calculation: delta op delta hp (oncotic pressure gradient hydrostatic pressure gradient) Positive nfp filtration (filtering out into isf) Negative nfp absorption (absorbing into capillary: example: arterial side: 37 25 = 12 mmhg, venous side: 12-25 = -10mmhg, at arteries filtration occurs into the interstitial fluid, and at the venous side, In the overall body, 20l of fluid is filtered across capillaries into ecf the fluid is absorbed back into the capillary.

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