BIOC33H3 Lecture : Shock, Systemic Inflammatory Response Syndrome
25 Mar 2013
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Document Summary
Chapter 67: shock, systemic inflammatory response syndrome, and multiple. Shock is a syndrome characterized by decreased tissue perfusion and impaired cellular metabolism resulting in an imbalance between the supply of and demand for oxygen and nutrients. Shock can be classified as low blood flow (cardiogenic and hypovolemic shock) or maldistribution of blood flow (septic, anaphylactic, and neurogenic shock). Cardiogenic shock occurs when either systolic or diastolic dysfunction of the pumping action of the heart results in compromised cardiac output (co). Precipitating causes of cardiogenic shock include myocardial infarction (mi), cardiomyopathy, blunt cardiac injury, severe systemic or pulmonary hypertension, cardiac tamponade, and myocardial depression from metabolic problems. Hemodynamic profile will demonstrate an increase in the pulmonary artery wedge pressure (pawp) and pulmonary vascular resistance. Clinical manifestations of cardiogenic shock may include tachycardia, hypotension, a narrowed pulse pressure, tachypnea, pulmonary congestion, cyanosis, pallor, cool and clammy skin, decreased capillary refill time, anxiety, confusion, and agitation.
