BIOC19H3 Lecture Notes - Lecture 9: Seminiferous Tubule, Leydig Cell, Spermiogenesis
Document Summary
Bioc19- animal developmental physiology: morphology, head: acrosome and nucleus (contains genetic information, mid-piece: has mitochondria which provides energy for movement of the tail, microtubules composed of 9 + 2 array. Differentiated sperm are sent to central lumen and all move to epididymis. From there, they move to ductus epididymis: function, travel independent motility, egg fusion mechanism of transfer of dna to egg, protection protect sperm dna during transport. Why is spermatogenesis a good model system: many seminiferous tubules in a single teste; abundant amount of cells of all stages for spermatogenesis; sperm is highly specialized. Spermatogenesis phases: spermatocytogenesis triggered by testosterone, diploid spermatogonia (immature sperm cells) undergo mitotic and meiotic divisions to form haploid cells from diploid cells, spermiogenesis morphological and molecular/biochemical transformation sequence that forms. Spermiogenesis mature sperm cells (spermatozoa: want sperm head to be smaller and compacted so it"s easier to swim (less resistance). Final sperm cell is highly differentiated by its unique property of independent motion.