BIOC17H3 Lecture 9: BIOC17-Lecture-9

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Bioc17: fairly rigid structure that lies just outside the plasma membrane and is covered by the glycocalyx. Cell wall functions: shape of the cell (cocci, rods etc, osmotic protection (containment to turgor pressure), protection against antimicrobials, pathogenicity. Two major groups of bacteria based on gram staining. Gram negative bacteria has a thinner peptidoglycan compared to gram postive. Periplasmic space= space between the two membrane that contains peptidoglycan in gram negative, in the gram positive that space would be in between the peptidoglycan and plasma mebrane. The outer membrane: formed by lipids, phospholipids, lipopolysaccharide (lps) and lipoproteins, braun"s lipoproteins connect outer membrane to peptidoglycan, porins (very important for permeability properties) Outer membrane structure & properties: two leaflets each made of two different lipids, lipopolysaccharides (lps) (only found in gram negative bacteria, phospholipids. Lipopolysaccharide: the major constituents of the external leaflet of the outer membrane, o specific polysaccharide / o antigen / o side chain, core polysaccharide lipid a.

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