BIOC17H3 Lecture Notes - Lecture 8: Tetrapeptide, Antimetabolite, Gram-Negative Bacteria
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Summary: the third amino acid on one tetrapeptide strand is linked to the fourth amino acid of an adjacent tetrapeptide strand this links the glycan backbone. Meshwork confers a shape and rigid structure to the bacterial cell. Amino acid three shows more variation but is also usually a product or an intermediate of lysine biosynthesis e. g. ll-dap, l-lysine, l-homoserine amino acid 3 is often species specific. Stem peptides results in a looser murein meshwork in the gram positive. Here are the chains and there are peptides holding the peptidoglycan together. This is 4 amino aid and the difference between gram negative and gram positive is that gram positive have an interbridge result looser mesh work. It can alter the bacterial cells to adhere. Gram negative has the outer membrane with polysaccharides on the outside. Small difference in murein chemistry e. g. nature of amino acid 3 can result in differences in the adhesiveness of the bacterial cell.