BIOC17H3 Lecture Notes - Lecture 4: Montmorillonite, Stromatolite, National Institutes Of Health
5 Oct 2017
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It was necessary to find something in common between birds and microbes. Lets look at ribosome: carl woese: to develop an universal phylogeny, it was necessary to find anuniversal beak, an element that is conserved and plays the same role among every group of organisms, including microorganisms. So, decided to look at ribosomes: used the gene that encode 16s rna and 18s rna as the universal beak. You find differences but still need to correct them. Identify different species and strains: presence of signature sequences: short conserved sequences that can be highly diagnostic of group of related organisms, aside!! All strains of e. coli are same species: crisis of pure culture: direct observation of natural samples of microbes always revealed more microbes than those that could be cultured. Uses 16s rrna: slide 26: as years progressed and with new technology, we identified new divisions in domain bacteria, before 16s rrna tool, there were only cultured divisions.
