BIOC16H3 Lecture Notes - Lecture 10: Colobinae, Gene Duplication, Yellow Emperor
25 Apr 2013
School
Department
Course
Professor
Document Summary
Will not allow any mutation at all so essential for the protein. The peak tells us that we should sequence this region in a variety of individuals from population and also assess their phenotype! Predict these with increased longevity would have deft sequences in this region than those with short life spans. Original view was that new genes always arose from duplication! The best way to study evolution of new genes is to rst identify recently eveolved genes and then infer their origin! Drosophila -jingwei (long and langley 1993 science)! Jingwei is a fusion of two parental genes: - ymp yellow emperor and -adh! Jingwei is -retroposition of adh mrna plus exons and introns from ymp! New duplicate under very strong positive selection! Digestive system of leaf eating colobine monkeys (zhang et al 2002, nature genetics) Rnase1b - max ef ciency of ph 6 (ph of colobine gut) !
