BIOB10H3 Lecture 3: lec 3 Studying Cells
Document Summary
Definitions: (1) heterodimer (a+b) vs (2) homodimer (2 of the same proteins) Level of structure primary absolute sequence of aa from amino end to carboxyl end peptide bonds secondary results from interactions btw backbone portions of adjacent or nearly adjacent aa. H bonds tertiary results from interactions within a single chain btw r groups or btw r groups at a distance and backbone. H bonds, disulfide bonds, ionic bonds, hydrophobic interactions. Because the fundamental properties of all cells have been conserved during evolution, the basic principles learned from experiments on one type of cell are generally applicable to other cells. Several kinds of cells and organisms are used as experimental models: S. cerevisiae (yeast) single celled eukaryote nucleus. Understanding of dna replication, genetic code, gene expression, and protein synthesis derive from studies of e. coli. Yeasts simplest eukaryotes easily grown from a single cell used for genetic manipulations similar to bacteria.
