BIOB10H3 Lecture Notes - Lecture 9: Immunoglobulin Light Chain, Golgi Apparatus, Inner Membrane
Document Summary
What is the cytoskeleton: f luid matrix surrounding organelles, extensive protein network. Proteins translated in cytosol and stay there by default : some examples: Clathrin and cop proteins : proteins outside of the vesicles. Made on free ribosomes in the cytoplasm, no targeting sequence: three main components, microtubules, actin, intermediate filaments. Cytoskeleton -functions: scaffold structural support and cell shape, i n ternal framework organize organelles within a cell, movement directs cellular locomotion and movement of materials within the cell, machinery for cell division, structure and support. Intracellular transport: contractility and motility, spatial organization. Structure: hollow, cylindrical, set of globular proteins arranged in rows : profilaments, contain 13 proto filaments. A- and b- tubulin subunits: subunits polymerize to make microtubules, b- tubulin binds gtp to allow polymerization, polymerize into proto filament. 13 proto filaments arrange around a hollow core and forms the microtubule = entire rod like structure. Protofilament = strings of those alpha beta www. notesolution. com.