ANTC67H3 Lecture Notes - Lecture 2: Complications Of Pregnancy, Myelin, Child Mortality

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When the construct is associated with several diseases. E. g. , cutoff for high blood pressure ( 140 mmhg systolic / 90 mmhg diastolic) is arbitrary because there is a coninuous increase in risk of cardiovascular disease at each level. Depending on the context (e. g. simple deiniions may be jusiied when there is a need. Case deiniion for rapid detecion and treatment: operaional deiniion for determining the presence of a disease, desired characterisics: Clearly and concisely ariculated, easy to use. Measurable in a standardized manner in diferent circumstances by diferent people. **in contrast, clinical deiniions involve use of clinical judgment. Die at each stage: the denominator must only include persons who are suscepible to (at risk for) the outcome, e. g. , a study looking at the occurrence of uterine cancer should exclude: Size of populaion at risk during ime period: use: Measures disease events (transiion from non-diseased to diseased) More useful for tracking disease when ime of onset is known eg.

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