PSY397H5 Lecture Notes - Lecture 7: Retrograde Signaling, Atomic Orbital, Nitric Oxide

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Multiple pulses one after the other pre synaptic releases glutamate binds to post. Nmda receptor and lasts long enough because of binding it depolarizes the post so with the two coinciding, 2 stimuli for that synaptic connection, tectonic can cause same response. Anatomical changes allow the brain to strengthen and weaken certain connections. Structural changes of the synapse itself, which make it more or less efficient and infers the strengthening and weakening of certain connections. Action potential to go to post synaptic neuron and chemical that transfers the. Efficient synapse higher chance of creating action potential when stimulated. Post generate an action before or after induction. After tetanus a smaller amount of epsp and still get spike, so it does. Synapse becomes more and more efficient that epsp is so high it can trigger and action potential, induce the epsp that is spread apart temporal summation does not occur. Immediate that lasts a few minutes, early then late.

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