PSY290H5 Lecture Notes - Lecture 3: Oligodendrocyte, Neuroglia, Dementia
Document Summary
Left image is a typical excitatory neuron: right = inhibitory, pyramidal neurons would be multipolar. Life support: connects with the axon hillock, cell body is integrating all that information and it is also converting it into an ap. Its aspects of dendrites and spines that are changing more than any other part of a neuron. Axonal membrane: our axons have channels that only open when there is a difference in charge, voltage-gated channels. Ligand-gated channel: something has to bind to channel for it to open, ligand, axons use a combination of voltage-gated and ligand-gated channels, neurons are energy consumers. Tau phosphorylation: microtubules are bound and tied together. In some people, as they age, they make too much tau protein. Its one type of neuron that is particularly affected: acetylcholine neuron, the brain looks like its being shriveled up. Glia/neuron ratio: we have an equal number of neurons to glial cells, oligodendrocytes myelinate our cns neurons.
