ANT202H5 Lecture Notes - Lecture 13: Zygosity, Sickle Cell Trait, Weaning

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4 ways humans respond to environmental stresses: cultural practices and technology (i. e. migration) Too successful = detrimental global environmental change: biological responses. Physiological adjustment of individual organisms to different conditions. Vs acclimation = changes occurring in response to artificial/controlled situation. E. g. temperature changes imposed in experimental manipulation. High altitude = increased respiration, increased heart rate, increased red blood cell production. Immediate (1-2 hours of exposure): fades during first 24 hours. Delayed (2-3 days of exposure): can last several months. Anatomical or physiological changes occurring during growth or development. Plasticity ability of organisms to respond physiologically or developmentally to environmental stresses. Migration to high altitude at early age. Genetic changes that develop in populations over long periods of time. Who 2015: 214 million cases, approx 438,000 deaths. Horticulture ideal for growth and spread of mosquito. Sequence of normal (hb a) and sickle cell (hb s) alleles. Mutation in beta chain of hemoglobin molecule. Homozygous for hb s = sickle cell anemia.

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