HSS 3305 Lecture Notes - Lecture 3: Rheumatoid Arthritis, Appendicitis, Serous Fluid
19 Oct 2015
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Document Summary
Inflammation is a non-specific response of body to local tissue injury. It is part of the body"s second line of defense. Functions of inflammation: cleanse injured area of debris and pathogens, prevent spread of injurious agent, set the stage for healing. Inflammation can also produce devastating effects (e. g. rheumatoid arthritis) Infection microbial agents: physical agents trauma, radiation, temperature, chemicals acid, alkali, toxins. Immune reaction auto, allo, allergy suffix itis used to indicate inflammation in a certain tissue (e. g. appendicitis) The inflammatory response can be acute and self-limiting or chronic and self-perpetuating. An introduction to inflammation inflammation and immune defense in overview of their function and. Histamine: released from platelets, mast cells and basophils (fast acting, but lasts less than 30 min, causes contraction of endothelial cells of blood vessels creates gaps in the walls to increase permeability. Bradykinin: similar to histamine, but slower acting, also activates nociceptors.
