HSS 3305 Lecture Notes - Lecture 5: Immunoglobulin M, Apoptosis, Colostrum

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 3305
• Professor: Karen Philips

Document Summary

Components: t4 lymphocytes (cd4+, b lymphocytes, plasma cells, antibodies (more golgi"s to help produce this) Human leukocyte differentiation antigens: clusters of differentiation (cd, gene that produce mhc class 1 and 2, antigens on outside of cell classified cd on more than 320 leukocyte surfaces. Function: regulate cell development and function, helps in recognition and development, communication, etc with extracellular environment. Il 1 helping to promote activation from the antigen presenting cell, il1 inducing proliferation. B-lymphocytes: differentiate from l(cid:455)(cid:373)pho(cid:271)last"s, develop in the bone marrow (t- thymus, b= bone marrow, have their own receptor, express cell surface immunoglobulin (ig) receptors which recognize specific antigenic epitopes: b cell receptor (bcr) also immunoglobulin. Cell surface: membrane bound ig, complement component receptors, do(cid:374)"t ha(cid:448)e to re(cid:373)e(cid:373)(cid:271)er the cd"s, cd expression is acquired during b-lymphocyte maturation, different immune cells have different combinations that allow different communication pathways to exist.