HSS 2342 Lecture Notes - Lecture 36: Aldosterone, Fluid Balance, Metabolic Waste

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Regulation of fluid and electrolyte balance are also regulated at two sites: gi tract minerals are reasorbed from food and digestive juices, kidneys by way of adh and aldosterone regulate electrolytes. Blood volume and pressure: role of the kidney. <1% of the filtrate is excreted as urine with the remaining 99% being reabsorbed into the blood. A kidney contains 1-1. 5 million nephron (functional unit) Glomerulus: the capillary (cid:374)etwork i(cid:374) the bow(cid:373)a(cid:374)"s capsule, glomerular capillary network acts as a filter in removing water and other substances (electrolytes, glucose, amino acids, and metabolic waste products) from blood. Causes of imbalance: prolonged vomiting or diarrhea, heavy sweating, burns and traumatic wounds, some medications. Solutes lost depend on why fluid is lost i. e. sodium usually lost during vomiting and potassium due to changes in aldosterone. Replacing lost fluids and electrolytes: usually water and healthy diet is best option. Ph is maintained within a narrow range: deviations can cause death!

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