HSS 2342 Lecture 7: Nutritional Determinants of Health - Chapter 7
4 Apr 2018
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Transfer of energy atp: energy is captured in the high-energy storage compound, atp, negative charges of phosphate (p) groups are vulnerable to hydrolysis, cleaving p groups releases energy, coupled reactions, catabolism and anabolism. Metabolic helpers: enzymes, almost always required, facilitate reactions, remain unchanged, coenzymes, complex, organic molecules, not proteins, associate with enzymes, required for enzymes to function. Metabolism overview: glycolysis: glucose-to-pyruvate, a little atp is used to start glycolysis, galactose and fructose enter glycolysis at different places, but all continue on the same pathway. Glycolysis of one molecule of glucose produces two molecules of pyruvate. High energy demand), pyruvate-to-lactate: why is pyruvate in muscle converted to lactate and not directed to the tca what circumstances cause this, working muscles break down most of their glucose molecules anaerobically to pyruvate. If the cells lack sufficient mitochondria or in the absence of sufficient oxygen, pyruvate can accept the hydrogens from glucose breakdown and become lactate.
