HSS 2342 Lecture Notes - Lecture 10: Gastric Bypass Surgery, White Adipose Tissue, Brown Adipose Tissue
1 Mar 2017
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Energy in = energy out is a bit of a lie. People have set point weights, the body tends to rebound to this weight after gaining or losing weight. The body is really good at not losing weight because it could be dangerous, especially in early humans. Despite size of fat cells decreasing, the number of them will not go down. Lpl brakes down the fat into fatty acids. Insulin will tell cells to keep fat and not release it. Fat mobilization just means the fats ready to move. The last point is true in all body tissues. Hypothalamus tells us if we are hungry or not. Body"s bmr can actually change to get back to set point. As we get older the epigenetics became more influential. Eating more and more over time can result in an epigenetic change and an. Obese person"s hypothalamus would undergo much more methylation increased set point.
