HSS 2305 Lecture Notes - Lecture 1: Henrietta Lacks, Cervical Cancer, Hela
Document Summary
A disease is often just a stress response. Cells are smallest unit of life: can be grown in a lab independently of a tissue. Cancer cells are easiest to do this. Henrietta lacks (hela) are the first immortal cell line from cervical cancer cells. Cells that grow well can be used for many experiments: cells are very tightly controlled, high degree of conservation in cellular organization and function across species, genetic material in cells. Allow for genetic mutation and variation: cells make and use energy. Most energy goes toward breakdown and rebuilding of macromolecules. Extensive turnover of molecules within the cell: engage in mechanical activity using motor proteins. Transport materials, assemble/disassemble structures, mobility: respond to stimuli using internal and external receptors alter cell movement, metabolism, death, capable of self regulation. Occurs during embryonic development: cells still have much in common despite differentiation.