HSS 2305 Lecture Notes - Lecture 8: Small Interfering Rna, Dicer, U2Af2
7 Oct 2016
School
Department
Course
Professor
Document Summary
At the end of the lecture the student should be able to: Explain why cells with the same genetic information can look and behave so differently. Identify key strategies used by eukaryotes to regulate gene expression. Emphasize importance of nuclear protein and rna trafficking, transcription factors and specific dna sequences in transcriptional control of gene expression. Explain how regulation of mrna splicing occurs and how this process would regulated gene expression within a cell. Emphasize importance of translational regulation, mrna localization within a cell and mrna stability in translational control of gene expression. Describe the role of rna interference in normal and pathological cell biology, and how these processes can be utilized in a research setting. Explain how the regulation of protein integrity can impact gene expression within a cell. Every cell contains same genetic information stored in dna: stem cell and cloning experiments. Only a subset of gene are expressed at any given time in a certain cell.
