HSS 1100 Lecture 5: Virus Work Sheet with Review Questions-2

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: Franco Pagotto

Document Summary

Viruses require living cells for growth and replication. Basic components: nucleic acid = infectious genetic material, protein coat = protection, surface antigen = protein or carbohydrate and highly variable. Five steps of replication>hsv 1 replication: adsorption, penetration and uncoating, nucleic acid and protein synthesis, assembly, release. How do we detect viral infections: detect the virus itself, detect the immune response . antibodies against the virus, respiratory viruses, influenza viruses. Type a: major epidemic, most virulent, causes most severe disease. Type b: milder disease, high recombination rate, need vaccine annually: parainfluenza viruses. Characterised by croup (barking cough: respiratory syncytial virus. Major respiratory pathogen for children under 2 years: rhinovirus = common cold, adenovirus. Pharyngitis and conjunctivitis; pneumonia in young children most commonly infected. Multiply in gi tract , but rarely cause gastro-enteritis . Poliomyelitis: highly infectious, invades the grey matter in the cns and can cause total paralysis in as little as a few hours.