HSS 1100 Lecture Notes - Lecture 2: Gastric Acid, Lactoferrin, Mucous Membrane

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: Franco Pigatto

Document Summary

Immunity = the protection against infectious disease conferred either by the immune response generated by immunization or previous infection or by other non immunologic factorsa. k. a. body"s ability to resist infection. Non specific: innate immunity (or natural: skin - mechanical barrier. Lower temperature that is suboptimal for some bacteria. Acid ph : sebaceous secretions and sweat contain unsaturated fatty acids (bactericidal) Cilia in respiratory tract (eliminates particles larger than 5 microns (e. g, large bacteria- carrying dust particles) Ph- e. g, gastric juice ph, acid ph in vagina, urine. That bind the iron necessary for bacterial growth. Polymorphonuclear white blood cells and monocytes as well as fixed macrophages in the tissues engulf and eventually destroy bacteria. Complement is a complex system of plasma proteins that work together to resist bacterial infection. Complement has two major roles, one on its own and one to enhance the immune response. Mecahnisms aimed at particular infecting organisms are divided into two major systems: