HSS 1100 Lecture Notes - Lecture 7: Respiratory Tract Infection, Echovirus, Elisa

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: Franco Pagotto

Document Summary

Require living cells for growth and replication (cell cultures, embryonate eggs, living animals/plants) Multiply by separate synthesis of nucleic acid and protein, combine to form virus particles. N. a. in capsid (protective protein shell) which is decorated in antigens. Capsid plays role in delivering to role. 1. adsorption - virus has to attach and uses the antigens. 2. penetration and undoing - releasing n. a. N. a. and protein synthesis - we need to use the cell to make a bunch of it. Assembly and maturation - n. a. and proteins put together. 5. release many more viruses released to go on and infect other cells. Pushed out gently - microscopy will work. Will be positive no matter how long oeuvre had it. Detect the immune response antibodies against the virus! Problem - may not have had the virus long enough to have had the antibodies. Antibody detection, presence or absence (elisa), immunity test.