BPS 1101 Lecture 8: Vaccines

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Cannot store large amounts of antibodies (small amount of many different types. No way to know which microbes will invade. Body stores small amounts of as many different antibodies as possible. Each b cells carries a different antibody (each b cell recognizes 1 epitope) (cid:271)od(cid:455) (cid:272)arries (cid:373)a(cid:374)(cid:455) differe(cid:374)t (cid:271) (cid:272)ells (cid:894)do(cid:374)"t k(cid:374)o(cid:449) i(cid:374) ad(cid:448)a(cid:374)(cid:272)e (cid:449)hi(cid:272)h are i(cid:373)porta(cid:374)t(cid:895) Store s(cid:373)all a(cid:373)ou(cid:374)ts of ea(cid:272)h b (cid:272)ells re(cid:272)og(cid:374)ize as (cid:373)a(cid:374)(cid:455) epitopes as possi(cid:271)le. Immune response triggers replication of specific b cell. After infection, some b cells become memory cells (to fight off infection in future) More memory cells stored as you get older. Less than 5% of b cells in a newborn are memory cells (sick more often) More than 50% of b cells in adults are memory cells (sick less often) Viruses live inside cells and escape b cells. Body makes t cells to destroy the viruses (have receptors that can tell when there is a virus)

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