BCH 2333 Lecture Notes - Lecture 13: Riboflavin, Hydrolase, Atp Hydrolysis

• School: University of Ottawa
• Department: Biochemistry
• Course: BCH 2333
• Professor: Christopher Boddy

Document Summary

Enzymes are classified and named according to the nature of the chemical reactions they catalyze: oxidoreductase, oxidation-reduction reactions, substrate reduced by addition of two hydrogen atoms while coenzyme. P450: a- + b a + b, transfer of electrons between molecules, nadh or fadh2 (ketone to alcohol, transferase, transfer of functional groups, e. g. Kinase- adds phosphate to alcohols e. g. g6p formation: a-b + c a + b-c, transferring part of molecule to another (group transfer) generate atp, Gtp: hydrolases, hydrolysis reactions, h2o as substrate, peptide (amide) bond cleaved by reaction w water, enzyme classified as hydrolase, e. g. Trypsin breaks to make amine cooh, acetylcholine esterase: a-b + h2o a-h + b-oh, lyases, group elimination to form double bonds, cleaving 2 bonds making a double bond, e. g. Pal, synthase in reverse: no atp, a-b a=b + x-y. G6p, g1p metabolism, phosphoglucose mutase: ligases, bond formation coupled w atp hydrolysis, 2 things put together (similar to reverse of 4.