BCH 2333 Lecture 4: DGD 4 - Protein structure
8 Feb 2017
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Document Summary
Rigid and planar due to double-bond character. Glycine has more conformational freedom because of its r group h atoms. Proline is restricted because phi angle can only rotate so much because it"s part of a. Alpha helix (3. 6 13 helix) 13 membered ring formed by single hydrogen bond (most. Representation to figure out what residues are concentrated on what side of an alpha helix. Parallel (not as stable, bend lines for bonds) Sheets are pleated due to phi and psi angle restrictions. R groups alternate in which side of the sheet they project. May be connected by hairpin turn parallel strands require an extended crossover connection. The proline glycine duo in the middle introduces a kick there is a hairpin turn here. Every alternating residue is polar, nonpolar, polar, nonpolar, etc. Up down up down one side is polar, one side in non polar in the beta sheet. Look for potential turns (glycine and proline)
