APA 2312 Lecture Notes - Lecture 4: Motor Control, Sarcolemma, Axon Terminal

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If in the book, but not menioned in class, should not be on exams. Both oral and lecture slides are exam material. Graded potenial: if a chemical simulates the sodium channel, transmembrane potenial is changed. Can increase or decrease transmembrane potenial, or result in ap (if threshold is reached) Inside becomes more negaive when sodium leaves cell, creaing a negaive tmp (only looking at k+). Also few na+ channels, allowing sodium to leak in, resuling in rmp of -70mv. Not an equilibrium created, but a staic state. Chemical need for channel to open or close. If threshold is not reached, potenial will return to rmp. If threshold is reached, channels react and open to change in rmp. Sodium rushes in, tmp becomes more posiive (around +30mv) Change in tmp acivates potassium channels (responding to electric charge), but are delayed in opening. Mostly na+ chemically-acivated ion channels in the soma (where ap starts) K+ channels open, bunch of molecules rush out.

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