ANP 1107 Lecture Notes - Lecture 1: Gastric Inhibitory Polypeptide, Gastric Mucosa, Portal Vein

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1107
• Professor: Jackie Carnegie

Document Summary

Gi tract expands to form stomach; temporary storage tank; initiate protein/food chemical breakdown convert to chyme; movable in between. 15-25 cm long; 50 ml-4l volume capacity; collapses inward & throw mucosa/submucosa into large, longitudinal folds (rugae) when empty; Stomach is innervated by autonomic ns: sympathetic fibers from thoracic splanchnic nerves through celiac plexus, parasympathetic fibers from vagus nerve. Arterial supply: arterial branches (gastric & splenic) of celiac trunk; corresponding veins part of hepatic portal system + drain into hepatic portal vein. Muscularis & mucosa modified; muscularis externa has an incomplete inner layer of smooth muscle fibrils running oblique; allow stomach to mix food & ram to small intestine (oblique fibers turn stomach into v-shape; propel action in pyloric part). Mucosa lined by simple columnar epithelium composed of goblet/mucous cells; produce protective. 2 layer alkaline mucus coat (viscous, insoluble) traps bicarbonate-rich fluid layer; lining has gastric pits (mucous cells) lead to tubular gastric glands (produce gastric juice).