ANP 1106 Lecture Notes - Lecture 3: Cell Membrane, Tight Junction, Lipid Bilayer

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1106
• Professor: Balwant Tuana

Document Summary

Constructed largely of phospholipids, with smaller amounts of glycolipids and cholesterol. This molecule has a polar head that is charged and is hydrophilic, and an uncharged, nonpolar tail that is hydrophobic. The polar heads are attracted to water, so they lie on the inner and outer surfaces of the membrane. The nonpolar tails avoid water so they line up in the center of the membrane. Lipids with attached sugar groups found only on the outer plasma membrane surface. Proteins that allow the cell to communicate with its environment. There are two distinct populations of membrane proteins: integral and peripheral proteins. Most are transmembrane proteins, which protrude through both the intracellular and extracellular regions. However, all integral proteins have hydrophobic and hydrophilic regions. This feature allows them to interact with both the nonpolar lipid tails buried in the membrane, along with the water inside and outside of the cell.