ANP 1106 Lecture Notes - Lecture 3: Endochondral Ossification, Coagulation, Osteoporosis

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1106
• Professor: Brianne Thrush

Document Summary

Bone is a living dynamic tissue that responds to its environment: stores calcium- resorbed and transferred to bloodstream when needed, bone reacts to amount of force applied by increasing density and amount of roughening on bone. Functions of bone: support, protection, movement, mineral and growth factor storage: calcium and phosphate, blood cell formation: hematopoiesis occurs in the red marrow cavities, fat storage, hormone production: osteocalcin regulates insulin secretion. Compare the structure of bony tissues and cartilages. Cartilageo tough and flexible: avascular, no nerve fibers, ground substance has lots of gags, collagen fibers, up to 80% wawter. Perichondrium: ct layer surrounding cartilage, contains blood vessels that provide nutrients to cartilage, in damaged areas it forms scar tissue. Chondroblasts: immature cartilage cells, actively form cartilage. Lacunae: small localized cavities with clusters of chondrocytes in cartilage. Description: hard, calcified matrix containing many collagen fibers; osteocytes lie in lacunae.