ANP 1106 Lecture Notes - Lecture 2: Root Hair, Cardiovascular Disease, Hirsutism

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1106
• Professor: Brianne Thrush

Document Summary

There are two distinct regions of the skin: epidermis: epithelial layer, thick keritanized stratified squamous epithelium, dermis: connective tissue, vascularized. Sun exposure increases melanin production: dendritic cells: langerhan"s cells (star shaped) migrate to epidermis from bone marrow, macrophages activate immune system, tactile cells: merkel cells, at the epidermis/dermis boundary, have disc like sensory nerve ending, touch receptors. Four major layers in epidermal thin skin: stratum corneum: outermost, dead cells, flattened out filled with keratin, connected by tight junctions and desmosomes, hold up to a lot of wear and tear and keratin waterproofs the body, Has stratum lucidum: clear layer, 2-3 rows of clear flat dead keratinocytes, corneum, lucidum, granulosum, spinosum, basale, dermis, on soles of feet and palms, no colour. Dermis has all the normal ct cells (fibroblasts, macrophages, mast cells, wbcs semi-fluid matrix with a lot of collagen, elastin and reticular fibers supplied with nerve fibers, blood and lymphatic vessels.